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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASTN2 All Species: 18.18
Human Site: S889 Identified Species: 50
UniProt: O75129 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75129 NP_054729.3 1339 148243 S889 K I L T K E S S R E E L L S F
Chimpanzee Pan troglodytes XP_528403 1357 150757 S907 K I L T K E S S R E E L L S F
Rhesus Macaque Macaca mulatta XP_001098403 1338 148255 S888 K I L T K E S S R E E L L S F
Dog Lupus familis XP_538814 1187 132903 Q746 D E L L S F I Q H Y G S H Y V
Cat Felis silvestris
Mouse Mus musculus Q80Z10 1352 149372 S902 K I L T K E S S R D E L L S F
Rat Rattus norvegicus XP_002726585 1354 149556 S904 K I L T K E S S R D E L L S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515531 1305 145285 F856 G A T S R G D F V A L L D Q F
Chicken Gallus gallus XP_426626 1355 150279 F907 G A T S R R D F V A L L D Q F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002660894 751 83839 F310 F V S I L K E F G N H F I Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 99 86.2 N.A. 96.8 96.2 N.A. 47.3 47.5 N.A. 27.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.7 99.4 87.6 N.A. 97.8 97.7 N.A. 64.2 65.2 N.A. 39.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 93.3 93.3 N.A. 13.3 13.3 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 26.6 26.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 23 0 0 0 0 0 0 0 23 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 23 0 0 23 0 0 23 0 0 % D
% Glu: 0 12 0 0 0 56 12 0 0 34 56 0 0 0 12 % E
% Phe: 12 0 0 0 0 12 0 34 0 0 0 12 0 0 78 % F
% Gly: 23 0 0 0 0 12 0 0 12 0 12 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 12 0 12 0 12 0 0 % H
% Ile: 0 56 0 12 0 0 12 0 0 0 0 0 12 0 0 % I
% Lys: 56 0 0 0 56 12 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 67 12 12 0 0 0 0 0 23 78 56 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 12 0 0 0 0 0 34 0 % Q
% Arg: 0 0 0 0 23 12 0 0 56 0 0 0 0 0 0 % R
% Ser: 0 0 12 23 12 0 56 56 0 0 0 12 0 56 0 % S
% Thr: 0 0 23 56 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 12 0 0 0 0 0 0 23 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 12 0 0 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _